Three Important Things to Know About Radicava

The ALS Association is the largest charity for people with Lou Gehrig’s disease in the United States. Not only do they provide excellent patient provision through care takers and support groups, they are also the leading fundraiser for new research when it comes to ALS treatment and a possible cure. During the summer of 2014, the ALS Association’s Ice Bucket Challenge went viral online and raised over 100 million dollars. This was the largest amount of donations the fundraisers at ALS had ever seen. They were ecstatic! This boost in funding led to the research and development of three new treatments for Lou Gehrig’s disease, one being Radicava, which will likely be available August of this year. Here’s what you need to know:

  1. Radicava slows the progress of ALS by reducing oxidative stress in the body. ALS is essentially a slow reduction in the body’s ability to function overall. This eventually leads to the shutdown of vital organs within the body. One of the first signs of ALS is the presence of oxidative stress, which is an imbalance between the presence of toxins in the body and the immune system’s ability to detoxify. These effects will first manifest themselves as a general slowing of autoimmune abilities followed by the more sinister effects of ALS, such as major organ failure. Radicava offers a time out to these unfortunate realities. The new medication has been shown to slow oxidative stress, and most patients see a 33% reduction in the decline of their physical abilities. Additionally, all Radicava test patients had higher scores on the ALS Functional Rating Scale
  2. First new medicine in 22 years. Because the origins of ALS are still largely misunderstood, it is incredibly difficult to approve and test new medications. Since the mid nineteenth century, our knowledge of what causes ALS has not kept up with other medical advancements. Because of this, it is incredibly difficult to find funding for new treatments when legislatures do not understand the medicinal premise. The first and last drug to be approved for treatment of ALS was Riluzole, which slowed lung failure. Unfortunately, the relatively small benefit offered to ALS patients compared to its astronomical costs essentially relegated Riluzole to pipe dream status. The mystery surrounding its origins combined with a lack of funding lead to a two decade ASL treatment dry spell. However, after the 2014 Ice Bucket Challenge, three new medications were presented to the FDA for approval. The first to reach the pharmaceutical market will be Radicava in August!
  3. Administered by infusion. At this point you’re probably wondering how Radicava will be administered to patients. Is it overly intrusive or painful? Will it even be worth it? For those who participated in the testing of the drug, Radicava absolutely is. The treatment is administered intravenously over a fourteen day period, followed by a fourteen day rest. After the initial treatment, patients will receive injections for ten out of every fourteen days. While this is a time-consuming treatment, this is the first ASL medication with legitimate promise for, not only extending the lives of those with Lou Gehrig’s disease, but also improving their quality of life!

After so many years of failed treatments and questions surrounding the origins of ALS, Radicava’s approval is a beacon of hope for patients and their loved ones.

Types Of Genetic Disorders

Genetic disorders occur as a result of abnormalities or variations in the information encoded by the genes and chromosomes. As per the available information on genetic disorders, these disorders can be broadly classified into four different categories, which are as follows:

1. Single-gene Disorders: Also known as Mendellian or monogenic disorders, these occur when the changes or mutations occur in only a single gene. Some well-known examples of single-gene disorders include cystic fibrosis, sickle cell anemia, Marfan syndrome, Huntington’s disease and hereditary hemochromatosis. Single gene disorders can be further classified into autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive and Y-linked disorders.

2. Multifactorial Genetic Disorders: Also known as polygenic, these disorders occur as a result of mutations in multiple genes. These disorders are really complex, difficult to analyze and hard to treat. Some examples of multifactorial disorders include autism, coronary heart diseases, cleft palate, mental retardation, cancer and diabetes.

3. Chromosomal Disorders: These diseases occur as a result of abnormalities in the chromosomal structure such as missing or presence of extra copies of chromosomes. The most well-known chromosomal disorder is the Down syndrome or Trisomy 21 where a person has three copies of chromosome 21. Other examples include Klinefelter syndrome, Cri-du-Chat syndrome, Turner Syndrome and Williams’ syndrome.

4. Mitochondrial Disorders: These disorders occur when there are mutations in the mitochondrial DNA or the non-chromosomal DNA of the cell. These disorders are maternal in origin as only egg cells contribute mitochondria in a developing embryo. One very good example of a mitochondrial disorder is the Leber’s Hereditary Optic neuropathy.

American Health Care Industry – Why Innovation is So Difficult

Healthcare industry presently in United States is in miserable condition, the delivery of treatment to consumers is often inefficient, ineffective and consumer unfriendly. The problems in the sector had been well documented and they range from medical errors, which by some estimates contribute around 8 percent of all deaths in United States, soaring cost of health care administration, the amount of time one get an appointment with the physician and inadequate facilities.

Why there are no innovations in the industry to improve it

Despite enormous investments in innovation and magnitude of the opportunity for the innovators, not many people are willing to invest in the industry. The reasons are numerous but one of the primary reasons is failing of too many efforts. Not many companies have able to translate their paper plan in the real world. One example of a massive failure is, managed care revolution that ended up losing $40 billion of investors’ money into biotech venture and into endeavors of achieving economies of scale to fragmented physician practices.

How we can improve present state of American health care industry

The idea of universal coverage is in rounds in public domain for years now, and there are no signs that Bush administration will take such restructuring of the system. The second solution to the problem is to focus on particular areas rather than solving the problem at once. These areas can be chosen carefully by the company according to its expertise and core competency. Some of the areas to focus which companies can zero down on are –

Innovations in the delivery of health care can result in more convenient, effective and less expensive treatments for today’s time stressed and increasingly empowered health care consumers.

New Drugs, diagnostic methods and drug delivery system can offer the hope of better treatment and care at lesser cost.

Healthcare is still astonishingly fragmented industry and integrated health care activities can increase efficiency, improve care and save consumer time.

What Is Olympics Cupping Therapy?

Through Olympics cupping, designed for athletes you cannot only enhance your blood flow but at the same time reduce muscle tension and promote the cell repair. It is even beneficial for connective tissues and aids in the formation of new blood vessels present within them. Athletes make use of cupping services by sports physiotherapy center to heal a host of conditions and aliments.

Different Types of Cupping
In the ancient era, cupping was performed with the help of animal horns. Later different cups made up of ceramic and bamboo evolved. Effective suction through these cups was possible with the use of heat, the cups were first heated in fire and then applied. Once they were cooled, they drew the skin due to pressure difference.

Modern cupping utilize cups that are crafted from glass and are rounded like balls. The two main types of cupping include:

  • Wet Cupping
  • Dry Cupping

In wet cupping a combination of medicines and suction is used to treat the patient, while for dry cupping only the suction method is implemented. Your preferences, present condition and the problems that you are going through help you choose the appropriate one.

What To Expect From Olympics Cupping Treatment
During the treatment, a specialized cup is placed on the skin and the vacuum sucks the muscle upwards. This creates a pressure onto the vessels, allowing the muscle to relax and relieves tension. The cups are usually allowed to settle for a period of 5 – 10 minutes after which they are removed and placed at another part of the skin. The process continues until a particular segment of the body has been rejuvenated by the cupping session.

To help athletes make the most of it, practitioners combine the power of cupping along with acupuncture to treat skin issues, digestions and other associated problems.

Cupping is able to cure a wide range of conditions that athletes often suffer at some point or the other and these include:

  • Facial Paralysis
  • Lumbar disc herniation
  • Herpes Zoster
  • Cervical spondylosis

The best part about this therapy is that it has zero side-effects or risks, allowing you to attain a perfect body without any complications.

But, before you begin with your cupping session do make sure that you consult with qualified practitioners about your conditions, past medical records and your expectations from the treatment. Because this ancient integrative medicine requires the support of both practitioners and patients in order to achieve successful results.

Beyond Aromatherapy

Aromatherapy in its simplest definition is the smelling of vapors for health & well-being effects, howsoever gained. This article examines a cross-section of the art and proposes a future course of direction for those professionals not wishing to be tarred with an aromatherapy brush.

Of course the fragrance of a nice perfume will leave you in a better frame of mind than the smell of rotting cadavers. The general intuitive appeal of a nice smell (etc) has launched a blind universal hype on essential oils, the mainstay of aromatherapy. Over the years it has attracted a large following of uncritical persons eager to believe good news. By contrast it has produced research well beyond the scope of aromatherapy.

Much opposition has been leveled against the wild claims that border on or even cross the line of fraud. Where there’s money to be made, there is opportunism. The truth is often the first casualty.

Then there is the medical profession. They are the stalwarts to uphold and defend the medical truth. Unfortunately there is opportunity to denigrate the practice of aromatherapy for motives other than altruism, leaving academia to the rescue. Disappointingly, much academic research is in effect unavailable to the general public as good research papers can be expensive.

Deserved or otherwise, alternative medicines such as Acupuncture, Ayurveda, Chiropractic, Homeopathy, Kinesiology, Light Therapy, Phrenology, etc. have been slow to gain traction in mainstream medicine. Within each field there may be something worthwhile. There is risk of throwing the baby out with bathwater.

Aromatherapy by semantic definition is in lockstep with things smelled, the nose being solely equipped to perceive things smelled. Thus aromatherapy armoury consists solely of essential oils. “Essential” not because we can’t live without them but because essential is merely the adjective from the noun “essence” being a vapor from a liquid at a low boiling point.

This semantic deception taken together with people such as those involved in routinely claiming these potions to cure things like ADHD, arthritis, high cholesterol, lupus, asthma, migraines, cancer, fibromyalgia confuses even more. It is there, on offer, all without the rigours of scientific validation. Long Live The Placebo!

Then there are the others making ambiguous claims that leave lots of wiggleroom such as “cleanses air of negative energies”, “restoring harmony and balance between the mind and body”, “restore psychic energy flow”, “return to one’s center and chakra”. These and more have become aromatherapy’s articles of faith in some circles. Most are seen as nonsense to the mind versed in scientific methods.

Contrast these with Moss et al in the peer-reviewed paper “Aromas Of Rosemary And Lavender Essential Oils Differential Affect Cognition And Mood In Healthy Adults” where they showed the efficacy of Lavender and Rosemary oils. 144 persons took part in the study and no one was informed of the study nature. Before and after inhalation tests included 15 words to be flashed on a screen for 1 second and participants were asked to remember as many words as they could in the space of 60 seconds. More tests were done using 20 photographs enabling researchers to test recall and reaction time.

Nominal recall improved from 5.5 for the control group to 6.2 for the Rosemary and showed little change for the Lavender. Nominal reaction time improved from a score of 246 for the control group to 259 for the Lavender. Little change was reported for the Rosemary tests. They concluded that essential oils can significantly affect aspects of cognitive performance.

Worth considering is a paper by Sayorwan et al, who, using electroencephalography (EEG), measured the changes in blood pressure, heart rate, and respiratory rate before and after Rosemary oil inhalation by uniformed groups of subjects and controls. Their findings provided evidence that brain wave activities, autonomic nervous system responses, and mood states could all be modified with Rosemary

Aromas may well have a placebo effect and as such it is a good thing. However it is not the smell that gives essential oils their efficacy but the compounds that comprise the oils. Compounds such as Eugenol, Carvacrol, Thymol, Geraniol, and Menthol appear to stimulate while Linalool appears to calm or relax. Then there is Eugenol, a very powerful antioxidant as well. These compounds can enter the bloodstream via the olfactory system and the lungs through breathing. The bloodstream can also be fed via the skin by massage and contact patches. Other possible routes are ingestion and intravenous injections. The latter are subject to much more research than currently appears in the literature.

In conclusion, the subject of essential oils is therefore a much wider field, rich with potential discovery. Thus it is important that practitioners who prescribe the use of essential oils in their practice divest themselves of any stigma that has grown around aromatherapy. A whole new name for their practice would help to distance themselves from any hint of quackery and dogma.

The general public may well be sceptical as a result of conflicting opinions. The misnomer “essential” does not help. Volatile Oil Therapy (VOT) as a name may engender some trust especially if the practitioners of VOT confine themselves to proven effects.

Regenerative Medicine and the Thymus Gland

In the field of modern medicine, debilitating musculoskeletal injuries are becoming less of a threat to long-term vitality thanks to advancements in knowledge of the body’s own intrinsic recuperative mechanisms. Now, increasing awareness about the body’s own healing processes has revealed a vital but still poorly understood regenerative mechanism initiated by the thymus gland. While still undergoing extensive study, clinical research has revealed its function in physiological protection and regeneration. Proteins produced by the thymus gland play key roles in rehabilitation and recuperation from all types of musculoskeletal injury.

Thymus proteins are produced naturally by the thymus gland early in life, with most production ceasing before the onset of puberty. Also referred to as Tβ4, they exhibit a myriad of cellular functions that assist the repair and recovery of wounded tissue. These include the enhancement of new blood vessel formation (angiogenesis), cell migration, stem cell differentiation, and gene expression. When the body suffers a physical injury (for example, a torn quadriceps), these proteins are found in greater concentrations near the wounded area, where they facilitate healing through the aforementioned mechanisms. Clinical studies have shown them to consistently facilitate the healing and recovery of damaged bodily tissue.

For instance, a 1999 study published in the Journal of Investigative Dermatology found that the thymus gland accelerates wound healing through the process of angiogenesis. Researchers observed that treated subjects’ wounds contracted by a minimum of 11% more than control subjects’ wounds by the one week mark. Though the study was conducted on rats, the researchers concluded that the thymus gland was a wound healing factor with multiple activities.

Further, a 2014 study in the Journal of Orthopaedic Research showed that the thymus gland was able to enhance bone fracture healing in mice test subjects. The study found that treated mice had a 41% increase in peak force to failure and had up to 26% more new mineralized tissue than the control group. Importantly, researchers noted that the findings of their study indicated that thymus proteins played a key role in the healing of bone fractures.

Moreover, additional studies have demonstrated that thymus proteins have potent anti-inflammatory effects as well. A 1999 study published in Nature Medicine sought to explore the action mechanisms of Tβ4 as anti-inflammatory agents. After the study’s conclusion, researchers noted that the thymus may have far-reaching effects on the body’s inflammatory processes.

Certainly, research on the thymus gland’s healing mechanisms may have a beneficial impact on our knowledge of the body’s regenerative processes. Again, though still in the early phases, clinical study to this point has shown the thymus gland to be a key part of the body’s natural recuperative mechanisms. Currently, several research centers are invested in further clinical study to yield greater knowledge of the thymus gland.

Healthcare Scenario of Bangalore

HEALTH SERVICES

The health-care scenario in Bengaluru city is a mix of plenty and scarcity. A number of government bodies and schemes provide health services. In infrastructure terms, if all primary health facilities maintained by different government bodies were combined, there are likely to be enough centers to 2 Health care in Bengaluru city – need for a participatory, comprehensive health plan meet the primary care needs of the population. The city is also host to autonomous institutions with high caliber medical professionals, such as National Institute of Mental Health and Neuroscience (NIMHANS) and the Jayadeva Institute of Cardiology. Further, like in other urban areas, a huge private sector caters to the health needs of the population.

Bengaluru is a hub for medical tourism, with super-specialty hospitals boasting state-of-the-art treatment facilities. On the other hand, the communities that particularly need public health services, such as the urban poor and working classes, are unable to access them due to the shortage of medical staff, lack of medicines and diagnostic services, high levels of corruption and the low sensitivity towards their needs. They end up using the private sector, which is an expensive option, or postpone essential health care – an even more expensive option for which the individual, family and society pay a price. There have been cases of women delivering babies at home or in auto-rickshaws as they were turned away at Maternity Homes and did not have time to reach a secondary or tertiary institution, or the resources to get there. Tertiary care is expensive even in government hospitals due to bed charges, medicines and other expenses. The result is high levels of indebtedness and health indicators among the urban poor that are almost as bad as the rural poor.

Government hospitals have a few advantages over private hospitals, which make them better and efficient for patients. This includes their facilities are affordable in cost, which is an advantage for the masses, who cannot afford expensive treatments. Best doctors are majorly found in the southern part of India. Bengaluru has a few government hospitals that make them stand out in other private ones.

In order to make health care available to the weaker sections of society Bengaluru is dotted with numerous government hospitals. Most of the government hospitals in Bengaluru are run and managed by the municipal corporation of the city. The government hospitals in Bengaluru are usually multi-specialty hospitals

Understanding Arthroscopy Surgery

Arthroscopy can be the solution to many types of arthritis and various injuries inside the joint. Also called as key hole surgery, it is the minimally invasive procedure used to examine the inside structure of the joint for the diagnosis and treatment.

The instrument used for this is called arthroscopy. The surgeons can view the area using the video monitor to diagnose and treat the joint tissues. Majorly all the joints in the body can be examined using the arthroscopy. Apart from examining the joint if any other procedure is performed using this, we call it arthroscopic surgery. This kind of surgeries requires lesser recovery times and pain. The tissue trauma will also be minimum. Because of the benefits, it offers arthroscopy is becoming essential for many orthopedic surgeries.

In the arthroscopy procedure, there is no blood loss expected and will have no or minimal complications. Only small incisions are made to examine and insert the arthroscopy. There is no need for opening the joint fully. The incisions are relatively very small and should be maintained dry for few days. And after the surgery, the patients need to stay for little time in the hospital will be recommended different exercises for strengthening the joints.

As said above, arthroscopy is considered in treating many types of arthritis like non-inflammatory and inflammatory. For example, patients with rheumatoid arthritis who have isolated joint swelling can be benefited with this by removing the inflamed joint tissue and examining it to discover any type of infections. This helps the doctors get more information where the diagnosis is difficult just by analyzing joint fluid alone for treatment.

Arthroscopy is also used for treating many knee joint injuries like ligament strains, meniscustears, posterior cruciate ligament, ligament strains etc; not only to treat knee joints and arthritis, arthroscopy is also considered to treat and examine many hips, wrist, feet, spine, ankle and elbow conditions. The arthroscopy is used to treat the wide range of sports injuries involving hips, wrists, ankles, and elbows as well.

Using arthroscopic procedures we can treat spine conditions like spinal deformity, tumors, spine trauma, spine disc herniation and degenerative discs.

The common conditions we treat using arthroscopy include shoulder dislocations, inflammation in knees, shoulders, elbows, and ankles, unstable shoulders, cartilage tears, rotator cuff tears, arthritis and shoulder joint degeneration, shoulder capsule release, cartilage tears and many more.

Arthroscopy surgery is generally performed by orthopedic surgeons. Even though it is a low risk surgery it is highly recommended to get it done by the expert surgeons for the speedy recovery and complete results. So considering arthroscopy over traditional surgery to treat any of the above conditions will assure the patients less pain, minimal complications and faster recovery.

Hernia Treatment Without Surgery Is Becoming Widespread

Generally, hernia requires surgery. But, these days, hernia treatment without surgery is becoming widespread. Yoga hernia exercises are useful for hernia treatment without surgery because it is found that over 30% hernia surgery patients end up with pain and discomfort afterwards. Inserting a foreign net can cause complications later in your 30 to 40 years of post-operation life. Instead of immediate surgery, you can try out gentle yogic stretching in static and dynamic form. This is good for gradually strengthening weak abdominal muscles as it supplies abundant amount of oxygenated blood that nourishes, activates, tones and strengthens. This in turn improves muscle tensile strength which prevent displacement of internal organs. Exercising as a solution for hernia will also safeguard that the hernia does not recur in adjacent area.

You can ask a physical therapist for guidance on exercises that fit your unique condition as patient education & training are key factors in the overall process of physiotherapy treatment. Hernia treatment without surgery will need 1 to 3 months of committed effort and patience to heal.

Piles

Piles are usually inflamed and swollen collections of tissue in the anal area. They can be of any sizes and may be internal or external. Piles are usually caused by increased pressure in the lower rectum. The blood vessels around the anus and in the rectum generally stretch under pressure and may swell, thus forming piles. The symptoms of piles are:

  • Hard stool and constipation,
  • Diarrhea and frequent bowel movements.

Doctors usually diagnose piles after carrying out some physical examinations like digital rectal examination or colonoscopy.

In most cases, piles dissolve on their own without the need for any treatment. But, some piles become severe. Read on to discover some piles treatment that will help significantly to reduce the discomfort and itching.

  1. Diet – Diet change is a must to keep the stools regular and soft. This means you need to eat more fiber, such as fruit and vegetables or bran-based breakfast cereals. You should increase water consumption.
  2. Body weight – Exercising and losing weight help in reducing the severity of piles.
  3. Medicines – Over-the-counter medicines like painkillers, ointments, creams, and pads help to soothe redness and swelling around the anus. Corticosteroids medicines can reduce inflammation and pain. Laxatives are prescribed if a person with piles suffers from constipation.
  4. Surgery – An elastic band is placed around the base of the pile, cutting off its blood supply. In sclerotherapy, medicine is injected to make the hemorrhoid shrink. Infrared coagulation is a device that is used to burn the hemorrhoid tissue. The excess tissue that is causing the bleeding can be surgically removed. Hemorrhoid stapling is done to block the blood flow to the hemorrhoid tissue. Laser surgery is the latest technique for treating piles.

So, multi specialty hospitals have well known doctors for piles treatment where you can get yourself completely cured.

A Hernia Is a Very Painful Disease and If It Goes Into the Last Stage, It Has to Be Operated

A hernia is a very painful disease and if it goes into the last stage, it has to be operated. There are many patients who prefer to go for surgery instead of continuing with the medication because it helps cure fast.

However, there is a different alternative to surgeries and it is becoming more and more popular among hernia patients. Technology has advanced in every possible way in the health section and doctors have come up with amazing solutions to make sure that you can get hernia treatment without surgery. This treatment involves controlling your diet plan, starting an exercise program and also wearing garments that would help heal a hernia. In fact, there are similar cures for piles treatment that doctors have come up with up in the recent time. But, what is it that will help you cure a hernia without having to go for the traumatic surgery? Let’s find out.

A systematic diet

One of the most important parts of treating a hernia without surgery is to have a good diet plan. Just like you have a diet chart when you want to lose weight, similarly there is a specific diet plan when you have hernia. However, it is important that you follow the diet religiously in order to quicken the process of recovery. Foods that are rich in fiber would be ideal for this situation. In addition to fiber rich foods, you should also include lots and lots of fresh vegetables and fruits. Since hernia patients lack minerals and vitamins in their body, it is essential that you eat food that are rich in vitamins and minerals and also zinc. All these will combine together to make collagen so that your skin gets the right amount of protein. A primary concern for hernia patients is their weak collagen content due to which the hernia occurs in the first place.

People exercise for various reasons, but for those who have a hernia, there are also exercises that helps to cure a hernia and prevent patients from undergoing a surgery. The exercises meant for hernia patients are mainly muscle exercises because the abdominal muscles have to be strained in order to cure the hernia. The main target area would be the muscles that lie just below the 6 pack. As those muscles are strained higher towards your stomach, the chances of curing your hernia increases. The most ideal exercise in this case would be Pilates as they directly deal with the abdominal muscles and will not only cure a hernia, but will also prevent it from growing any further.

Change in attire

That is the reason why many companies have come up with abdominal belts and pants that can keep your abdominal muscles tight. This in turn will help in ensuring that the hernia is prevented from getting worse.