A Detailed Insight on Symptoms of Piles

This condition is classified into two types which are:

  • Internal Piles: The internal piles occur within the rectum are not painful due to lack of sensing nerves. At times, it collapses and protrudes outside anal sphincter, which appears like moist pads of skin. This prolapsed haemorrhoids and can be treated with laser surgery for piles.
  • External Piles: The external piles are present in the anus and thus can be more uncomfortable. When this prolapses outside (due to the movement of stool) they become visible. Blood clots occur on them, leading to a painful stage known as thrombosis. When the external piles get thromboses it turns from pink to blue and could even bleed.

What Are The Causes of Piles?

An individual at any age can be the victim of piles. It is a common diseases, that affects over 50% of the people at some point or the other. However, they are usually seen during pregnancy or elderly age, when the haemorrhoids become weak. No matter what the cause behind this condition might be, getting the best piles treatment is of utmost importance.

The four situations that increases the chance of developing piles include:

  • Chronic Constipation
  • Ageing
  • Hereditary factors and
  • Pregnancy

In chronic constipation, excess pressure is applied on the rectum making the veins push against the wall of anus, resulting into feeble and weak anus muscles. This ruptures the haemorrhoids which bleeds making stools even tougher to eject. It is often accompanied with pain and sensitivity. In case of ageing, the tissues present across the lining area get less supportive and affect the haemorrhoids veins.

Similarly, in pregnancy the pressure of baby lying in the anus and rectum breaks the veins and causes piles. Other than that, in certain cases people have inherited weakness at the anal region that makes them prone to this condition.

Know More About the Symptoms of Piles

It must be noted that the symptoms of pile do vary and is influenced by the cause and nature of the condition.

Some of the common signs that are often faced by people are:

  • A feeling of hard lump at the anus region. It is usually coagulated blood that is often seen in external piles.
  • Bright red blood comes out after bowel movement
  • Discharge of mucus when bowels pas
  • A feeling of having full bowel, even after going to the toilet
  • Area around the anus turns sore and red and
  • Itchiness and inflammation at the affected area

A good practice is to consult with a doctor immediately when you come across at least two or more signs of piles.

Analysis to Next Generation Sequencing Technology

With the development of science, traditional Sanger sequencing has failed to meet new requirements of low cost, high throughput and fast in speed.

Recent years, with the discovery and promotion of second-generation sequencing technology, the gene sequencing speed has increased greatly while achieving a substantial decline in costs, making large-scale application of genome sequencing possible. Now, the cost of personal whole genome sequencing is about 5,000$, and is expected to decreased to less than $ 1,000 in the next few years.

The rapid development of sequencing technology will promote the massive accumulation of DNA sequencing data, accompanied by the accumulation of the corresponding individual diseases, signs and other data at the same time. When we accumulate enough data, how to understand these data will be critical. On the micro level, generations of molecular biologists’ studying the effects of apparent biological traits genes exert on utilizing technologies like gene knockout have made breakthroughs in many crucial aspects. On the macro level, statistics and other data analysis techniques are introduced to study the relationship between gene sequences and biological phenotype. The accumulation of basic scientific research gradually brings breakthroughs in clinical applications.

There are now two types of clinical applications mainly, one aims at disease screening of ordinary people. It infers people’s future risks of getting cancer by measuring the known genes associated with a disease loci. The other aims at the diagnosis cancer and other deadly diseases. It finds in a series of drugs or plans the most effective one for certain patients by testing the loci of certain genes.

Data from BBC research shows that total global gene sequencing market increased from $ 7.941million in 2007 to $ 4.5 billion in 2013, and will reach $ 11.7 billion in the year of 2018 with the CAGR up to 21.2%.

Currently, the market of de novo sequence platform is mainly taken by several major manufacturers, including the Illumina, Ion Torrent / Life Technologies (was the acquisition of Thermo Fisher in 2014), 454 Life Sciences / Roche, etc.

Under such a circumstance, the next generation sequencing technology (second-generation sequencing) appears. As an emerging industry, the next-generation sequencing technology can be applied in clinical testing like antibody discovery, health industry, industrial and agricultural use of gene-oriented study as well as scientific research and development.

To stimulate the next generation sequencing market, we need to start by investing more small and medium size industry focusing on this field.

Glomerulonephritis: How to Diagnose and Prevent It at Various Levels

Glomerulonephritis is an inflammation of the glomeruli in the kidney. The glomeruli is constellation of small blood vessels in the kidney that act as a filter to remove excess fluid, electrolytes and nitrogenous wastes from the blood into the urine.

It is divided into:

  • Acute Glomerulonephritis- The symptoms develop suddenly.
  • Chronic Glomerulonephritis- The symptoms develop gradually.
  • In glomerulonephritis, the glomeruli lose their filtering capacity thus blood proteins and red cells are excreted in the urine in various quantities depending on the severity of the glomerular damage.

DIAGNOSIS OF GLOMERULONEPHRITIS

Accurate diagnosis is essential in the successful treatment of glomerulonephritis.

Diagnosis is highly dependent on the clarity of symptoms, examination and investigation findings.

SYMPTOMS

  • Passage of coca-colored urine due to the presence of red blood cells in the urine. This is called haematuria.
  • Passage of foamy urine due to excess amount of proteins in the urine. This is called proteinuria.
  • Presence of peri-orbital and ankle swelling.

EXAMINATION FINDINGS

  • Peri-orbital and pedal edema.

ยท Elevated blood pressure.

INVESTIGATIONS

  • Urinalysis-This reveals diagnostic findings such as red blood cells, casts, white blood cells and proteins in the urine.
  • Blood test- Blood level of electrolytes, urea and creatinine. This is mainly done to assess the extent of kidney damage.
  • Radiological imaging tests-This is done usually when the blood tests suggest some level of kidney damage. E.g Renal scan or abdominal CT scan is done.
  • Kidney biopsy- This entails using a clinical procedure to extract some pieces of kidney tissues for microscopic examination. This is the only test that confirms glomerulonephritis.

TREATMENT

This is based on the following principles:

  • Treat underlying health conditions quickly.
  • Use of corticosteroids to reduce the degree of inflammation and immunological responses.
  • Dialysis- This is used for individuals with acute kidney injury or kidney failure.
  • Anti-hypertensives such as ACEI, ARBs- This is used to control hypertension in some selected individuals.

PREVENTION STRATEGIES

There are 3 levels of prevention namely: primary, secondary and tertiary.

PRIMARY PREVENTION

The aim of this is to prevent the onset of glomerulonephritis.

It entails the following:

  • Throat swab should be done for suspected bacteria cause of sore throat. If streptococcus is suspected, oral penicillin should be commenced as soon as possible.
  • Prompt treatment of individuals with bacteria endocarditis.

SECONDARY PREVENTION

This involves early diagnosis and prompt treatment of glomerulonephritis.

It specifically entails the following:

  • Routine urinalysis to be done periodically for individuals at risk of streptococci infections and for individuals greater than 40 years.
  • Periodic monitoring of blood urea and creatinine levels should be done for individuals with compromised kidney function.

TERTIARY PREVENTION

This involves activities and interventions put in place for individuals with glomerulonephritis from developing complications such as kidney failure and to reduce the disease progression.

  • Optimal control of co-morbidities like hypertension and diabetes mellitus.
  • Reduce intake of high protein diet.
  • Restrict salt intake.
  • Cessation of smoking.
  • Regular clinic follow up by a Nephrologist.

Finally, glomerulonephritis is a very lethal kidney disease of which the onset and progression can be prevented if an individual adheres to the activities in the various levels of prevention highlighted above.

Bringing Scientific Rigor to Medical Research Using Blockchain Technology

Blockchain technology applied to medical research can improve trust in science by creating an unchangeable, time stamped record of the research findings. Blockchain technology, invented by Satoshi Nakamoto in 2008, ensures that transactions entered into a ledger cannot be changed with time. As applied to the cryptocurrency bitcoin (BTC), the result is a monetary system that, cannot be manipulated by a centralized government because it creates a permanent and accurate record of all transactions. The strength of the system comes from its use of a distributed database as compared to current monetary systems that require a centralized database such as is used by credit card companies and banks. Applying this same technology to medical research increases trust in the results because just like bitcoin, the transactions (scientific data collected) are permanently archived in an unchangeable, immutable manner.

The exchange of money, just like the conduct of medical research, requires a high level of trust. Money in the past has generated this trust through government regulations and central bank oversight. Medical research in the past has attempted to create high levels of trust through peer review conducted by reputable medical journals such as the New England Journal of Medicine. Both methods of generating trust rely on a trusted central authority, either the government or a medical journal. As such, both methods are highly susceptible to fraud via corruption or innocent errors of the centralized authority. This has led to widespread distrust in medical research. Bitcoin operates differently, because it sets up a method of relying on a distributed network based upon a mathematical algorithm, rather than centralized authority susceptible to human error.

Financial transactions require perhaps the highest level of trust. People need to know that all transactions recorded in the ledger be entirely accurate and totally resistant to being changed in the future. Because blockchain technology as implemented in bitcoin has earned this trust, bitcoin has become a widely used store of value with a market capitalization of over $100 billion USD. When other cryptocurrencies are considered, the total trust in blockchain based financial systems exceeds $250 billion USD. Similarly, health care professionals need to be able to trust that data obtained from medical research is both completely accurate and completely immutable. Physicians need to know that medical research isn’t plagiarized or fraudulent in any way. Blockchain technology has made bitcoin a trusted, global currency. In the same way, blockchain based medical research will greatly increase trust in the results and as a result, improved medical care.

Aging Does Not Have to Mean Decreased Quality of Life Thanks to Holistic Medicine

One unavoidable facet of the human condition is the progression of time and the correlating health changes that go along with the passage of time. Those who are aging typically face conditions that weaken the body and reduce the quality of life as the years add up. There are various holistic approaches that can help these individuals tone their bodies and improve their quality of life again. These approaches avoid the prescribed medications of functional medicine and focus on other treatments that utilize natural compounds and therapy focused on movement and invigoration.

Healthy Eating Habits

Fruits and vegetables are important to help the body stay fit and operate as it should. Eating organic is a big boost to the body’s efforts to maintain strong muscles and healthy skin. Making sure to include the right amount of Vitamins C, D, E and K as well as Vitamin A will keep the body functioning as it should and help individuals enjoy their remaining years.

Supplements

Holistic medicine believes that providing the body with the natural compounds it needs, the body’s capabilities return to what they were in the individual’s younger years. It is important to take supplements rich in vitamins and anti-oxidants in order to help the body complete processes as it should.

Skin Care Taken Seriously

The first step is to minimize sun exposure and also cut down on the amount of chemicals the skin is exposed to on a regular basis. Next, it is important to use topical vitamin C and moisturizers to help the skin stay supple and healthy.

The aged look of skin can be addressed and reduced, provided you utilize the right products and don’t -buy into the promises from make-up or cleansers that are sold for profit and not for the true benefit of the consumers.

Exercise and Sleep Can Mean the Difference

It is important to get enough sleep and make sure to take proper care of teeth and gums. This allows the body to handle illness and any pain or discomfort as it should, rather than having the focus diverted to these issues or the energy available reduced due to lack of sleep.

For those who want to stay healthy, it is important to fit in some exercise, even if it is a regularly scheduled walk. The body needs the exercise to help burn fats and process certain compounds to remove them from the system.

Functional medicine revolves around a specified pain or condition, the diagnosis of said illness and prescriptions meant to resolve or at minimum keep the issue at bay. For those who want to feel healthy and avoid taking too many prescriptions, it is wise to turn to the holistic option to evaluate the potential answers for the condition the sufferer deals with on a daily basis. The prognosis may be better, and the sufferer may get more immediate resolution to the problem. A happy ending using natural solutions can be within reach quickly. Functional medicine has its place, but holistic medicine is an undervalued resource for those with chronic conditions.

Dental Health Activities

Dental health activities are designed to encourage good dental health practices and to help avoid dental cavities, gum diseases and oral cancer. State dental health programs are the primary entities responsible for conducting the core activities with regard to oral health conditions within different states. Local health departments in association with the dental community and public/private schools also arrange various dental health activities. The promotion of dental sealants and monitoring of the fluoride content in drinking water are examples of disease prevention activities. The American Dental Association provides a great deal of resources for dental health activities.

Classroom dental health activities are an integral component in the development of a child. Dental health activities to provide valuable oral care education and to promote the importance of proper dental hygiene among children are conducted with the help of posters, interactive dental health games and contests, health fairs and classroom presentations. Health educators present programs on topics such as brushing and flossing, bad breath, good nutrition and how to overcome the fear of visiting the dentist. The organization and administration of school-based fluoride mouth rinse programs and the promotion of school dental screening are examples of additional dental health activities focused on children.

Organizations such as Oral Health America develop, implement, and facilitate educational and service programs designed to raise awareness of the importance of oral health. Nationwide activities and campaigns coordinate schools, governments, care providers, and corporate and community partners in the fight against tooth decay and oral disease prevention. Many state dental health programs are involved in epidemiological surveys, applied research projects and community needs assessments. This information is important in developing an appropriate and responsive community programming. Many public health systems operate independent public health dental activities. These activities vary in scope and size across each state depending on population requirements. State grants are allotted to develop innovative dental activities and programs specific to individual states? needs, and improve access to oral health services.

Misuse of Medical Equipment

When doctors order tests like x-rays and CAT scans they usually only need a simple reason for doing so. Unfortunately, in many cases these types of health care equipment is misused or ordered when it is not really necessary. When this happens a patient ends up paying for a service they should not have had to. The costs alone from misuse of health care equipment is staggering. Not only is it putting a dent in the pockets of patients, but it is also part of the reason for rising health care costs.

Besides the financial side of misuse of health care equipment, there is the health concerns to consider. X-rays, for example, are known to be dangerous. A person is being subjected to radiation which can be profoundly damaging to the body. There is a limit on the recommended number of X-rays a person should receive, but many times when a doctor orders a x-ray, they are unaware of the person s history with getting x-rays. Additionally, x-rays are harmful for pregnant women and for reproductive organs, in general. Too many x-rays can lead to many health problems.

The misuse of health care equipment is something that is likely to go unnoticed. More and more insurance companies, though, are requiring further validation for such uses which may help to end misuse. However, most of the time as long as a doctor deems it necessary, the procedure will continue.

When it comes to medical equipment, x-rays are probably the most used type of health care equipment. In emergency rooms around the country, doctors usually are quick to order an x-ray if the diagnosis is not immediately recognizable. The misuse of health care equipment can lead to many problems for the patient.

The Health Care System is Broken – Should Big Parma Buy Hospitals?

We all know that the health-care system in the United States of America is broken and it doesn’t take a rocket scientist to figure that out. As podium pushers and politicians tell us that they will give us universal health care we all know that that is impossible. We also know that the Social Security system is running dry and we can barely afford that.

We know that there are all kinds of lobbyists from the health-care industry in Washington, DC trying to keep it going and keep the government paying for all these health services in our hospitals. The truth this is the Medicare system in the United States was originally ill-conceived and it is only gotten worse throughout the years. Today it represents a huge cost that we can no longer afford.

Indeed the health-care system is broken, but who is coming to the rescue and how come these politicians keep promising us universal health care – a scheme that would clearly bankrupt our nation? So who is going to bail out all the hospitals if the government stops footing the bill?

Maybe big Pharma and the pharmaceutical companies might buy up all the hospitals in order to make sure that those hospitals only sell their drugs? America is on drugs there is no doubt about that and the average Grandma now is probably taking 13 different medications all counter-acting each other, wow, now that is certainly quality of life.

It is incredible this crisis – maybe we should combine these two crisis – the health-care industry and big Pharma and put them together so we can manage them better as we cut off some of this excessive corporate welfare? Too hard hitting for you? So, what’s your solution then?

Tips On Reducing Health Care

When it comes to lowering your health insurance premiums it takes no rocket scientist to figure out how it’s done. If you’re trying to reduce your insurance premiums then you need to become less of a risk for the insurance companies. You can become less of a risk for insurance companies through exercise, eating healthy and preventative care.

If you’re not exercising at least three times per week then you have got to get on a program. A good program consists of you doing cardiovascular training three times per week for 45 minutes. You should be weight training at least twice per week for 30 minutes. For some, getting to the gym might be out of the question. If it’s difficult for you to get to the gym, then take up some other form of exercise including walking, running, hiking and sports.

If you’re not currently eating 5-6 meals per day then you have got to get on the band wagon. All nutritional experts agree on the principle of grazing throughout the day, taking in smaller portions for meals. When you are doing this you are allowing your body to digest food much easier thus creating a faster metabolism. When your metabolism speeds up then you are able to lose weight and get in shape. Along with eating five to six meals per day also remember to eat healthy. The best part about eating healthy is that there are many options for healthy food. The best tip for eating healthy is to keep it as natural as possible. Try to avoid processed food at all costs.

Preventative care is you being proactive with your body, and going in for a check-up if something feels out of place. Preventive care is you avoiding unnecessary risks that could jeopardize your health. This mindset is you acting, and not being acted upon. If you are truly exercising a preventative attitude then you won’t allow yourself to get obese or unhealthy, because you are in control of your future. If you exercise, eat healthy, and implement preventative health care, you will be able to not only live longer and healthier, but you will also have reduced your health care substantially.

Health Is Wealth, So Take Care of Yours

Health is what can be defined as the general condition of a human being concerning all aspects of his life. In general good health is acquired by means of a combination of physical, mental and the social comforts and securities. You have to realize that maintaining good health is a never ending process and you have to constantly be on the lookout for ways and means to stay healthy.

Hygiene is one of the main factors that constitute to good health. Keeping yourself clean and tidy which involves brushing, bathing, washing hands especially before a meal etc. The list is endless and all these contribute to your well being and health. If hygiene is a factor that helps improve health, stress can affect your health adversely. Stress management is imperative to remain in good health. If you are in a job that often has you completely stressed out, then give some relaxation techniques a try. They can help to relieve stress.

Health care can be described as the treatment and the management of the various illnesses both physical and mental that you may contract through the years. Today more and more people are becoming aware of the fact that health and fitness are of prime importance in life. This improves the health and fitness industry that come out with various types of fitness equipment that promise to keep you healthy and fit.

To live a healthy life you may have to make some changes in your lifestyle by consuming a nutritious diet, drinking more water everyday, increasing your intake of foods that can give you more roughage, putting a brake on the fried and processed food intake and incorporating a regular exercise regime like going for a walk daily. Remember you are not required to carry out any hectic work-outs. It is just to ensure that all parts of your body remain supple. This is especially necessary as you grow older and various aches and pains start getting you down.

Health is such a significant matter that you simply cannot let things just be. You have to make a deliberate attempt to be healthy and remain so.